Endocrine Abstracts

Aims:It is currently well known the pathogenic relationship between abdominal obesity(AO),impaired glucose tolerance(IGT)and insulin resistence(IR).We have proposed the studying of presence of a correlation between the obesity degree,established with the help of the body mass index(BMI)and of its type(indicated by the waist-hip ratio-(WHR)with a IGT frequency or of the non-insulin-dependent diabetes mellitus(NIDDM)and of the hyperinsulinemia(HI)in a bihor county population gro...

Objective:The clinical observations suggest that there is statistically significant correlation between Diabetes Mellitus(DM)type and the type of treatment on one hand, and the average duration of occurence of the chronic complications on the other hand.Material and Methods:The studied groups comprised that 1315 subjects who represent all the patients suffering from Diabetes Mellitus(DM),under the observation of Diabetic Center in Oradea.<p class="ab...

Objective:The clinical observations suggest that there is statistically significant correlation between Diabetes Mellitus(DM)type and the type of treatment on one hand, and the average duration of occurence of the chronic complications on the other hand.Material and Methods:The studied groups comprised that 1315 subjects who represent all the patients suffering from Diabetes Mellitus(DM),under the observation of Diabetic Center in Oradea.<p class="ab...

Giant cell tumors are rare, benign but aggressive and locally invasive tumors that usually affect the long bones in the limbs, typically presenting during the 3rd or 4th decade of life. Giant cell tumors of the skull are exceedingly rare, and less than 150 cases have been reported to date, of which less than 10 were described in the pediatric population. Here, we present the case of a 14 year old female that progressively developed severe headaches, blurr...

Pericentromeric inversion of the heterochromatic region of chromosome 9 has been reported in almost 4% of the cases of male infertility.Objective: Determining the karyotype from an infertile couple scheduled to perform IVF.Materials and methods: Slides with metaphasic chromosomes were GTG-banded according to standard protocol for cytogenetic analysis (karyotype). FISH analysis – inverted DAPI (4′-6-diamidino-2-phenylindo...

Introduction: Post-partum thyroiditis (PPT) is an autoimmune disorder of the thyroid gland, which occurs in the first year after parturition. Post-partum thyroiditis occurs in 50% of TPO AB+ve women and is characterised by transient hyperthyroidism followed by transient hypothyroidism during the first 6 months, post-partum. A third of the latter group develop permanent hypothyroidism. The aim of this study was to evaluate sonographic characteristics in a g...

Introduction: It is known that hypothyroidism has multiple etiologies including tyrosinkinase inhibitors (TKI) agents which can cause thyroid disfunction through different mecanisms, not fully defined yet- Vascular endothelial growth factor receptor (VEGFR) blockade, thyroiditis, iodine uptake blockade, increased activity of deiodinase 3, increased hormone clearance. Some recent trials suggest that there is a correlation between the incidence of hypothyroidism and the outcome ...

Background: Fahr syndrome is a rare entity characterized by symmetrical bilateral brain calcifications, involving basal ganglia (mainly), thalami, dentate nuclei and the cerebral and cerebellar white matter. Progressive neurologic dysfunction and other neuropsychiatric disorders are characteristic. Endocrine disorders which may present with Fahr syndrome include parathyroid dysfunction (hypoparathyroidism especially, but also pseudohypoparathyroidism, pseudopseudohypoparathyro...

Introduction: Follicle-stimulating hormone (FSH) and its corresponding receptor (FSHR) are essential factors for regular gonadal development, sexual maturation at puberty and gamete production during the fertile period in both sexes. The FSHR encoding gene was mapped to the short arm of chromosome (CR) 2 in 2p16.3.3 In females, inactivating mutations result clinically – depending on the degree of inactivation – in primary amenorrhea, sec...

Introduction: Follicle-stimulating hormone (FSH) and its corresponding receptor (FSHR) are essential factors for regular gonadal development, sexual maturation at puberty and gamete production during the fertile period in both sexes. The FSHR encoding gene was mapped to the short arm of chromosome (CR) 2 in 2p16.3.3 In females, inactivating mutations result clinically – depending on the degree of inactivation – in primary amenorrhea, sec...